Immunotherapy

Stomach (Gastric) Cancer

The stomach is an integral part of the digestive system and is located in the upper abdomen. It is attached to the esophagus at the top and the small intestine at the bottom. After you chew and swallow your food, food travels down the esophagus and enters the stomach, where it starts to digest due to the secretion of gastric juices. The partially digested food and gastric juices then empty into the small intestine for further digestion.

Stomach cancer, also referred to as gastric cancer, can start in any of the five parts of the stomach. Treatment of stomach cancer depends on the size and location of the tumor, as well as whether it has metastasized (spread) to other parts of the body. The lungs, bones and liver are common sites of metastasis. Your doctor will also consider other factors, such as your age and general health, before recommending one or a combination of treatments.

Treatment options include surgery, chemotherapy, targeted therapy, radiation therapy and immunotherapy.

Immune checkpoint inhibitors are drugs that block specific proteins and receptors from triggering a slowdown of the immune system. An immune checkpoint inhibitor targeting PD-1, a protein found on T-cells, may be used to treat certain types of stomach cancers.

 

FDA-Approved Immunotherapies for Stomach Cancer
As of 10/20/2017
pembrolizumab (Keytruda)

 

Additional Resources

 

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